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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPAG5
All Species:
8.18
Human Site:
T336
Identified Species:
18
UniProt:
Q96R06
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96R06
NP_006452.3
1193
134422
T336
G
R
I
L
G
S
D
T
E
S
W
M
S
P
L
Chimpanzee
Pan troglodytes
XP_001140543
298
34177
Rhesus Macaque
Macaca mulatta
XP_001108753
1196
134903
T338
G
R
I
L
G
S
D
T
E
S
W
M
S
P
L
Dog
Lupus familis
XP_537743
643
73062
Cat
Felis silvestris
Mouse
Mus musculus
Q7TME2
1165
129974
S316
S
R
I
P
G
L
E
S
E
T
W
M
S
P
L
Rat
Rattus norvegicus
NP_001037689
1187
132367
A329
P
G
P
T
A
E
D
A
S
R
I
P
D
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696012
1532
172515
P626
P
P
V
F
G
N
G
P
L
Q
E
Q
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q99323
2057
236625
L1025
E
E
E
R
V
L
A
L
G
G
E
K
K
K
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10567
882
101931
K138
A
M
N
V
L
R
K
K
H
Q
D
S
C
L
D
Sea Urchin
Strong. purpuratus
XP_001184407
626
68776
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAP9
779
87818
M35
E
I
Q
P
E
S
T
M
E
S
R
D
D
E
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.8
91.7
46.9
N.A.
65.3
62.3
N.A.
N.A.
N.A.
N.A.
21.6
N.A.
21.3
N.A.
21.9
20
Protein Similarity:
100
24.8
94.2
49.9
N.A.
77.8
75.3
N.A.
N.A.
N.A.
N.A.
41.5
N.A.
35.5
N.A.
39.7
34.3
P-Site Identity:
100
0
100
0
N.A.
60
6.6
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
0
100
0
N.A.
80
6.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
6.6
N.A.
6.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
0
0
0
28
0
0
0
10
10
19
0
10
% D
% Glu:
19
10
10
0
10
10
10
0
37
0
19
0
0
10
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
10
0
0
37
0
10
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
10
28
0
0
0
0
0
0
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
10
10
0
0
0
10
10
10
0
% K
% Leu:
0
0
0
19
10
19
0
10
10
0
0
0
10
19
37
% L
% Met:
0
10
0
0
0
0
0
10
0
0
0
28
0
0
0
% M
% Asn:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
19
10
10
19
0
0
0
10
0
0
0
10
0
28
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
19
0
10
0
0
10
% Q
% Arg:
0
28
0
10
0
10
0
0
0
10
10
0
0
10
0
% R
% Ser:
10
0
0
0
0
28
0
10
10
28
0
10
28
0
0
% S
% Thr:
0
0
0
10
0
0
10
19
0
10
0
0
0
0
0
% T
% Val:
0
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _